Western blot analysis showed that lncRNA BCRT1 knockdown could increase the expression of epithelial markers (E-cadherin) and decrease the expression of mesenchymal markers (such as Fibronectin, N-cadherin, and Vimentin) (Fig. 3d), indicating that lncRNA BCRT1 could regulate the EMT process to modulate breast cancer progression. This evidence concerns the gene CDH2 and breast carcinoma.