Cumulative urine flow and sodium excretion responses to GLP-1 were also decreased in HF rats (1951 ± 166 vs. 2451 ± 151 μl/gkw and 275 ± 25 vs. 351 ± 21 μEq/gkw at 60 min, respectively, P < 0.05, n = 10, Fig. 4c, d). Here, GLP1R is linked to hydrops fetalis.