Some exploratory studies evaluated specific antigen stimulated or un-stimulated serum cytokine biomarkers other than IFN-γ for monitoring the potential effect of anti-TB treatment, such as TNF-α, IL-10, IL-6, IL-1ra, MIP-1β, IL-2/IFN-γ and IP-10 [10–14]. Here, IFNG is linked to tuberculosis.