The levels of 16 cytokines including Eotaxin, MCP-1(MCAF), SDF-1α, MIP-1β, G-CSF, VEGF-A, Basic FGF, IFN-γ, TNF-α, TRAIL, IL-1α, IL-1ra, IL-4, IL-8, IL-9 and IL-17A were significantly higher in active TB patients compared with non-TB controls in both untreated and treated participants at T0. This evidence concerns the gene IL4 and tuberculosis.