This might be the causal factor for the reported developmental and language delay, neurobehavioral disturbances, and psychiatric problems, such as autism, seizures, and schizophrenia with occasional mild dysmorphic features seen to a varying degree in patients with the 15q11.2 BP1-BP2 deletion (Burnside–Butler) syndrome [1,36]. Here, IGFBP2 is linked to autism.