Thus, all four genes in this narrow segment between BP1 and BP2 are significantly associated with autism spectrum disorder, with an average of >68 MalaCards InFormaTion Score (MIFTS) with annotation strength (max 100) and with Solr (an open-source enterprise-search platform) relevance scores 0.171, 0.088, 4.578/0.377, and 0.21/0.094 for NIPA1, NIPA2, CYFIP1, and TUBGCP5, respectively (Table 4, Table 7, Table 10, Table 13, and Table 16). This evidence concerns the gene IGFBP2 and autism spectrum disorder.