PGP and chronic myelogenous leukemia, BCR-ABL1 positive: Moreover, EVs from drug-resistant chronic myeloid leukemia cells gave rise to an accumulation in recipient cells not only of P-gp and microRNAs (miR-27a, miR-451 and miR-21) related to P-gp expression, but also of the inhibitors of apoptosis proteins XIAP, IAP and survivin.