As RARα mediates the anti-proliferative action of ATRA in breast cancer cells [9], we exposed SK-BR-3 cells to ATRA, AM580 (RARα-agonist), UVI2003 (RARβ-agonist) and BMS961 (RARγ-agonist) (Figure 7C). This evidence concerns the gene RARA and breast carcinoma.