CSF3 and precursor B-cell acute lymphoblastic leukemia: Recent studies find that, the cytokines related to B-ALL progression, such as granulocyte colony- stimulating factor (G-CSF) that induces progenitor cells proliferation and differentiation to neutrophils, play a crucial role in malignant transformation of leukemia.[9,10] Consequently, more clinical data are necessary to construct and verify the model accuracy and repeatability.