CD4 and age-related macular degeneration: There was no statistically significant difference in CD4 cell counts (median [interquartile range], −116.9 [−242.3 to 39.9cells/mm3 for zinc vs −135.6 [−283.9 to −48.6] cells/mm3 for placebo; AMD, 41.8 cells/mm3; 95% CI, −20.3 to 103.8 cells/mm3; P = .19) or Reynolds Risk Score (median [interquartile range], −0.17 [−0.75 to 0.38] for zinc vs −0.14 [−0.95 to 0.55] for placebo; AMD, −0.014; 95% CI, −0.167 to 0.139; P = .85) between participants in the zinc and placebo groups (Table 2).