In 2012, two research groups identified the interferon induced transmembrane protein 5 (IFITM5) gene (MIM *614,757), which encodes bone restricted IFITM‐like protein (BRIL), as responsible for causing OI5 (Cho et al., 2012; Semler et al., 2012). The gene discussed is IFITM5; the disease is osteogenesis imperfecta type 5.