The sum of the three different cellular tau pathologies is the highest in the striatum and the thalamus/subthalamic nucleus and the frontal, parietal, and motor cortices (exemplified by PSP-RS, PSP-P, PSP-F, PSP-PI, see online supplemental file, Figs. 2, 3, 4). This evidence concerns the gene MAPT and supranuclear palsy, progressive, 1.