MET and neoplasm: ROC analysis for differentiating IDH1-mutant tumours from IDH1-wildtype tumours showed that the area under the curve (AUC) of the FLT T/N ratio (AUC 0.911, 95% CI 0.847–0.975; Fig. 3b) was significantly larger than that of the MET T/N ratio (AUC 0.727, 95% CI 0.607–0.847; Fig. 3a) (P < 0.01).