Incidentally Wu et al.[150] did report that prolactin (PRL), another member of the type 1 cytokine family similar in structure to GH, also conferred docetaxel resistance via ABCG2 upregulation in T47D human breast cancer cells in a JAK2-STAT5 as well as PI3K-MAPK dependent manner. The gene discussed is JAK2; the disease is breast carcinoma.