IFNA1 and systemic lupus erythematosus: When taking the three SNPs together, the accuracy was the highest with the cross-validation consistency of 10/10 (OR = 9.99, 95% CI 6.54-15.26, P < 0.001), indicating that the miR-181b rs322931 and IFNA1 rs1332190 and rs10811543 were interactively associated with the risk of SLE.