PTPN3 and skin basal cell carcinoma: Our findings revealed that CYFIP2 (AUC = 0.949), HOXB5 (AUC = 0.908), PTPN3 (AUC = 0.952), MARCKSL1 (AUC = 0.962), PTCH1 (AUC = 0.981), and CDC20 (AUC = 0.956) could significantly distinguish BCC samples and healthy controls, implying that these genes might serve as diagnostic makers for BCC detection (Figure 5).