CRP and Aortic dissection: Although previous studies also confirmed that high sensitivity CRP and D-dimer were associated with a poor prognosis in aortic dissection patients [26], these markers also exhibiting different time course of their changes in acute-phase reactions [27, 28], while three biomarkers that integrate multiple pathways of inflammatory and thrombotic processes, which may provide a better and more stable assessment of the prognosis of AAAD patients.