CDH2 and cancer: Principally, BCA deaths are caused by cancer metastasis.[27] Epithelial‐mesenchymal transition (EMT) is a developmental process that converts epithelial cells into mesenchymal and migratory phenotypes, which has been heavily implicated in cancer metastasis.[28] Several factors regulate EMT, including Snail, Slug (Snail2), N‐cadherin, and Vimentin.[29] To investigate the effects of ZY‐444 on migration and invasion, we conducted wound healing assays and invasion assays.