IL1B and chronic atrophic gastritis: For IL-1B-511 polymorphisms, TT genotype with H. pylori infection has been reported to increase the risk of gastric atrophy in high prevalence region of gastric cancer (Shanxi) in China [5] and the risk of GC in population with Han nationality (Hubei) [28], and TT/CT genotypes could increase risk of GC in Chinese population (Jiangsu [29] and Guangdong [30]).