CSF2 and tuberculosis: To determine whether the anti-TB activity of albGM-CSF was dependent on the intravenous route of administration, female C57BL/6J mice were first infected with Mtb by an aerosol route, and 4 weeks later, they were subcutaneously injected with either albGM-CSF or GM-CSF once every week for 4 weeks (Fig. 4b).