GFI1B and medulloblastoma: Most of the samples from a subgroup of medulloblastomas, especially those with highly expressed growth factor independent 1 family proto-oncogenes (GFI1 and GFI1B), had recurrent structural variations that resulted in the relocation of GFI1 and GFI1B into close proximity of foci occupied by active SEs, initiating oncogenic activity41.