We found significant correlations between IL-17 and IL-8 (r = 0.819, p < 0.0001), TNF-α and IFN-γ (r = 0.640, p < 0.0001), VEGF and IL-17 (r = 0.585, p < 0.0001), FGF-2 and GM-CSF (r = 0.5843, p < 0.0001), and VEGF and IL-8 (r = 0.545, p < 0.0001) in patients with AOSD. This evidence concerns the gene CSF2 and adult-onset Still disease.