In addition, they demonstrated that CB-ECFCs were able to decrease the expression of mediators of inflammation and atherosclerosis produced by allogeneic lymphocytes and monocytes (IL-1β, IL-8, PGF, ALOX-5, TNFα, CSF-2, MMP-1, MMP-9) more significantly than adult ECFCs [27]. This evidence concerns the gene ALOX5 and atherosclerosis.