To investigate whether SH3BGRL is related to breast cancer progression, we analyzed the gene dataset, GSE15852 on breast cancer and observed that the SH3BGRL expression in Invasive Ductal Carcinoma (IDC) is obviously higher than in adjacent normal tissue (P = 0.034) (Fig. 1a). Here, SH3BGRL is linked to breast ductal adenocarcinoma.