ANO1 and head and neck squamous cell carcinoma: Because TMEM16A is particularly known to be upregulated in head and neck squamous cell carcinomas (HNSCC), where CK2 also has a pro-cancerous role [43], we examined the hypothesis that CK2 promotes proliferation of the HNSCC cell lines Cal33 and BHY through activation of TMEM16A, which would have consequences for the treatment of HNSCC.