Some of these genes, like PTEN, FBXW7, or BIM, have already established tumor suppressive and pro-apoptotic roles [6,21,22,23], yet their interactions with hsa-miR-20b-5p and hsa-miR-363-3p have not been studied functionally in T-ALL thus far. This evidence concerns the gene FBXW7 and acute lymphoblastic leukemia.