Among 96 BRCA2 PV carriers, 69 individuals (71.9%) had female breast cancer, 14 of which bilateral (20.3%), 9 TNBC (13%) and 20 diagnosed before age 35 years (29%), 16 patients (16.7%) had ovarian cancer, 15 of which high-grade serous (93.7%) and 1 endometrioid (6.3%), 6 subjects (6.2%) had both primary ovarian and breast cancer, 5 patients (5.2%) had male breast cancer (Figure 1b; Table 1). The gene discussed is BRCA2; the disease is breast carcinoma.