MAPT and Cerebral cortical atrophy: This corroborates the previously reported associations between cognitive deficits in Alzheimer’s disease and the individual effects of tau pathology, neuroinflammation, and downstream cortical atrophy (Femminella et al., 2016; Bejanin et al., 2017; for reviews see Chandra et al., 2019; Melis et al., 2019).