Therefore, knowing that samples from divergent phenotypes were collected, considering the family history, it is possible to highlight that the genes, such as ACAN, MMPs, COLs, EPYC, VIT, LRRC15, CCBE1 and LGALS3 can be considered strong candidates for the development of umbilical hernia in pigs and in other mammals”. The gene discussed is EPYC; the disease is Umbilical hernia.