Also, the expression of MAP1LC3B, another gene from the MAP1LC3 family, was increased in humans with incisional hernia (IH), concomitantly with the enhancing of apoptosis signaling, affecting the cell death and ECM detachment process, which contributed to the appearance of hernias in the fascia of patients with IH [68]. This evidence concerns the gene MAP1LC3B and isolated hemihyperplasia.