Furthermore, three other genes were located in QTL regions already identified for scrotal/inguinal hernias [11,109]: ACAN, BCHE and KANK3. The ACAN gene, which has been previously mentioned, related to cell adhesion and extracellular matrix [49], has been pointed out as a potential gene involved in the occurrence of hernias. This evidence concerns the gene ACAN and Inguinal hernia.