From this set of genes, we highlight KRT14 (Keratin 14), CCBE1, ACAN, Desmoglein 2 (DSG2) and EPYC, which were more enriched in the anatomic development process in the gene network (Fig 7) and were upregulated in animals affected by umbilical hernia. The gene discussed is DSG2; the disease is Umbilical hernia.