We used a stepwise logistic regression method to establish the diagnostic model with a diagnostic formula of logit (P = HCC) = -5.58 + (5.84 × ENFA3 expression level) + (1.84 × EGF expression level) + (-1.04 × MMP3 expression level) + (18.10 × AURKB expression level). Here, EGF is linked to hepatocellular carcinoma.