To examine the value of these four angiogenic genes (ENFA3, EGF, MMP3, and AURKB) for the construction of diagnostic, prognostic and recurrence models, we analyzed the expression patterns of the angiogenic genes in the HCC cohorts from ICGC database and different online database, including cBioportal, UALCAN and Human Protein Atlas database. The gene discussed is AURKB; the disease is hepatocellular carcinoma.