TLR4 and obesity due to melanocortin 4 receptor deficiency: Diabetic phenotypes and increased levels of α‐hydroxy VLCFA‐GM3 species were ameliorated in HFD C3H/HeJ mice (Figs 7D and EV4E), suggesting that TLR4 signaling is partially involved in production of α‐hydroxy VLCFA species in obesity.