Similarly, a cross-sectional study reported that smoking accentuated the elevating effect of heavy alcohol drinking on TG in a male Chinese population suggests strong interactions between alcohol drinking and cigarette smoking on lipid profiles.15 Smoking also affects lipoprotein lipase activity, so it is involved in TG metabolism.31 Previous studies reported that smokers had significantly higher prevalence of hypertriglyceridemia than non-smokers.32,33. This evidence concerns the gene LPL and hypertriglyceridemia.