To determine if the improvement in forelimb motor recovery and induction of BDNF in the striatum following TAK-063 were associated with axonal sprouting after striatal stroke, the neuroanatomical tracer BDA was used to quantitatively map axonal projections from the forelimb motor cortex 6 weeks after stroke, a time of improved motor recovery (Fig. 1a). The gene discussed is BDNF; the disease is Stroke.