IL18 and adult-onset Still disease: As shown in Figures 2(e) and 2(f), significantly higher levels of IL-1β and IL-18 were observed in AOSD patients (median 5.0 pg/ml, IQR 2.2-83.5 pg/ml; 1088 pg/ml, IQR 590-7719 pg/ml; respectively) than in HC (median 2.1 pg/ml, IQR 1.4-3.1 pg/ml, p < 0.05; 109 pg/ml, IQR 70-152 pg/ml, p < 0.001; respectively).