Other corroborating evidences are the increased inflammatory markers (NF-κB, TNFα, IL-6, and IL-10) reported in cortical tissues of murine diabetes models [201–203], HK2 cell cultures under high glucose environment (NF-κB) [204], and cortical portions of T2D patients (NF-κB) [202]. Here, NFKB1 is linked to type 2 diabetes mellitus.