SLC5A2 and diabetes mellitus: SGLT2 has been studied in many models of diabetes, and the results suggest increased protein [32, 67, 84, 85, 90, 94, 99, 107–111] and mRNA [22, 32, 83, 85, 100, 104, 106–109, 112] contents and activity [108] despite some controversial results [85, 93, 98, 100, 105, 113].