PINK1 and Parkinson disease: Nearly 10% of PD cases may be caused by mutations in over 12 different genes implicated in the regulation of proteasomal degradation pathways (Parkin, ubiquitin carboxy-terminal hydrolase L1), mitochondrial homeostasis (PINK1, mitochondrial serine protease Omi/Htra, integral mitochondrial protein DJ-1, and leucine-rich repeat kinase 2), lysosome function (ATPase cation transporting 13A2 (ATPase cation transporting 13A2)), antioxidant response pathways (oncogene DJ-1 also known as a Parkinson disease protein 7) and mitophagy (PINK1 and Parkin) [7, 8].