CASP8 and cancer: In a systematic review of the plants being studied, some mechanisms were mainly common, including the induction of apoptosis by means of an increase of expression and levels of caspase 2, caspase 3, caspase 7, caspase 8, and caspase 9 in cancer cells, increasing the expression of the proapoptotic protein Bax and decreasing the expression of the antiapoptotic proteins.