In addition to their expression changes associated with wound repair [63], the cohort of SERPINE (plasminogen activator inhibitor 1), PLAUR (plasminogen activator, urokinase receptor), and PLAU (plasminogen activator, urokinase) are upregulated in psoriasis compared to amounts beneath the limits of detection or at very low levels in healthy epidermis [64]. The gene discussed is SERPINE1; the disease is psoriasis.