DFS was significantly associated with positive lymph nodes (p = 0.047), a tumour size ≥2 cm (p = 0.043), perineural infiltration (p = 0.006) and the staining of ITGB6 (p < 0.001) and SFN (p = 0.032) (Table 1B). Here, ITGB6 is linked to neoplasm.