HDAC7 and nasopharyngeal carcinoma: To explore the functions of HDAC7 in NPC, we first established HK1 and 5–8F NPC cell lines with stable knockdown of HDAC7 (HK1 shHDAC7 and 5–8F shHDAC7) by HDAC7 shRNA because both cell lines had high HDAC7 expression (Figs. 1c, 2a), and analyzed the effects of HDAC7 knockdown on NPC cell proliferation, migration, and invasion.