CBLN1 and type 2 diabetes mellitus: Higher levels of (dihydro)ceramides d17:1, d18:1, d20:1 and d18:0 increased the risk for T2D (eg, Cer d18:1 HR 2.38 (95% CI 1.81 to 3.12) per 1 SD), while lactosylceramides d18:2 and d18:1, on the other hand, reduced T2D risk (eg, HR 0.57 (95% CI 0.42 to 0.78) per 1 SD for lactosylceramide 18:1).