LRRK2 and Platelet storage pool disease: Post-hoc tests revealed that in comparison to Ctrl (median and IQR = 816 (596–1112) pg/ml, n = 43), levels of CSF t-α-syn were significantly lower in sPD group (median and IQR = 573 (466.5–710.5), n = 60) (P < 0.001, Fig. 1a), asymptomatic LRRK2 mutation carriers (median and IQR = 617 (431–803) pg/ml, n = 51) (P < 0.01, Fig. 1a), and symptomatic LRRK2 mutation carriers (median and IQR = 608 (432–740) pg/ml, n = 23) (P < 0.01, Fig. 1a).