Autosomal recessive mutations in the phospholipase A2 group 6 gene (PLA2G6) are causative for phospholipase A2-associated neurodegeneration (PLAN) syndromes, including classic infantile neuroaxonal dystrophy (INAD) and atypical neuroaxonal dystrophy with childhood-onset (atypical NAD), and adult onset APS called dystonia-parkinsonism, which is associated with Lewy bodies and neuroaxonal dystrophy (Table 1) [139, 157, 161, 249, 316, 370]. Here, PLA2G6 is linked to neurodegeneration with brain iron accumulation 2A.