AMELX and dental caries: One study [19] was omitted from the analysis of AMELX rs17878486 because the outlier data and the results illustrated that by deleting this study, the CT [OR = 3.07; 95%CI: 1.36, 6.94; P = 0.007; I2 = 0% (Ph = 0.37)] and CT + TT [OR = 5.72; 95%CI: 2.83, 11.59; P = < 0.00001; I2 = 21% (Ph = 0.0.28)] genotypes in dental caries patients were significantly superior to controls and with a low heterogeneity, respectively (Table 3).