Meanwhile, according to a previous research, age, gender, BMI, diabetes, pancreatic texture, the diameter of main pancreatic duct, abdominal surgery history, intra-abdominal bleeding, blood transfusion, pancreatojejunostomy, nutritional support, somatostatin, hypoproteinemia and other factors might also be related to the risk factor of POPF after PD [15, 16]. The gene discussed is SST; the disease is diabetes mellitus.