Having revealed that the combination of dinaciclib with EV-T stimulates drastically enhanced apoptosis in some cancer lines like A549, we therefore, next investigated whether already known anti-apoptotic proteins cFLIP, XIAP, Bcl-2, CDK1and CDK9, and pro-apoptotic protein Bax, are regulated by EV-T, dinaciclib or combination of the two agents in A549 cells. This evidence concerns the gene BCL2 and cancer.