Yuan et al. have shown that 6p21 and 15q25 loci, which are lung cancer risk-related loci, were enriched in lncRNAs including HCP5, RP11-650L12.2, XXbac-BPG27H4.8, and HCG17. Analysis of 17,153 cases and 239,337 controls pointed out that at least six HCP5 SNVs (including rs3130907 within the HCP5 sequence) were significantly associated with lung cancer susceptibility [142]. This evidence concerns the gene HCP5 and lung cancer.