By using the calculated optimized cut off values for all laboratory variables, we found bilirubin (hazard ratio: 0.746, 95% confidence interval: 0.610–0.913, p = 0.004), GGT (hazard ratio: 1.443, 95% confidence interval: 1.093–1.905, p = 0.010), ALT (hazard ratio: 0.791, 95% confidence interval: 0.658–0.951, p = 0.013), ALP (hazard ratio: 1.440, 95% confidence interval: 1.101–1.884, p = 0.008) and BChE (hazard ratio: 1.406, 95% confidence interval: 1.129–1.754, p = 0.002) to show a significant association with CSS (cancer-specific survival) in univariate analysis (Table 2). The gene discussed is BCHE; the disease is cancer.