The proband was injected insulin when he was diagnosed as MODY2; (6) There were two untreated probands (31) (59 and 48 years old) with FPGs 9.80 mmol/L and 13.66 mmol/L and HbA1c 7.8% and 9.2%, respectively. Here, INS is linked to maturity-onset diabetes of the young type 2.