Among all 72 EPTB cases, 10 (13.89%) had a previous TB treatment history, 21 (29.17%) were either ambulatory or bedridden functional status at enrollment, 26 (36.11%) were either at WHO stage III or IV, 54 (75%) had CD4 count <200 cells/μl, 18 (25%) had Hgb value <10 mg/dl, 33 (45.83%) were underweight, 40 (55.56%) did not take ART drugs, 66 (91.67%) did not receive IPT and 27 (37.5%) did not take the CPT (Table 3). This evidence concerns the gene CD4 and tuberculosis.