Using two different endothelial reporter mice (i.e., Tie2 and VE-cadherin) in combination with immunostaining for α-SMA and MYH11, Qiao et al. (2014) demonstrated the occurrence of EndMT in pulmonary vessels in an experimental animal model of PAH induced by monocrotaline and pneumonectomy. The gene discussed is ACTA1; the disease is pulmonary arterial hypertension.