Originally, Fabbri et al. (2012) demonstrated that miR-21 and miR-29a released by lung cancer cells bind to receptors of the Toll-like receptor (TLR) family (murine TLR7 and human TLR8) in immune cells; thereby promoting a TLR-mediated pro-metastatic inflammatory response. This evidence concerns the gene TLR7 and lung carcinoma.